In-Cell Dual Drug Synthesis by Cancer-Targeting Palladium Catalysts
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چکیده
منابع مشابه
Palladium Catalysts in Organic Synthesis
The main catalysts which are traditionally used for the hydrogenation of organic compounds are supported platinum group metals, and while these heterogeneous catalysts are generally not effective in carbon-carbon bond forming reactions, there has been a growing interest in recent years in soluble complexes of the platinum group metals for use as catalysts in organic synthesis. Rhodium catalysed...
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The synthesis of supported palladium (Pd) catalysts is reviewed with emphasis on the chemistry of catalyst synthesis, oxidic and carbon support properties and case studies in the period 1990-2000. For the application of Pd onto oxidic supports aqueous precursor solutions are frequently used. The charge of the Pd precursor and the iso-electric point of the support are important properties since ...
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متن کاملThe Development of Palladium - Catalysts for Organic Synthesis
Chapter 1. Suzuki-Miyaura coupling reactions of aryl and heteroaryl halides with aryl-, heteroaryl and vinyl boronic acids proceed in very good to excellent yield with the use of 2-(2',6'-dimethoxybiphenyl)dicyclohexylphosphine, SPhos. Additionally, a comparison of the reactions with SPhos and with 2(2',4',6'-triisoprocpylbiphenyl)-diphenylphosphine is presented that is informative in determini...
متن کاملSilica-Supported Palladium-Based Catalysts for Clean Synthesis
Research into supported palladium complexes is described. The complexes are immobilised on porous silica supports using both grafting and templated sol-gel techniques. The resultant complexes are efficient catalysts for various C-C bond forming reactions, including Heck, Suzuki and allylic substitution. The catalysts are stable and can be easily recovered and reused, making them suitable for cl...
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ژورنال
عنوان ژورنال: Angewandte Chemie
سال: 2017
ISSN: 0044-8249
DOI: 10.1002/ange.201702404